First of all, a good pair of socks is usually made of 50%~78% combed cotton for breathability and sweat absorption, accompanying a mixture of other materials to increase elasticity such as 3% DuPont Lycra.
Second, choose a reinforced foot base for extra cushioning around heels and toes areas.
Third, choose a pair of seamless socks whose toe part is hand-knit or knitted by leading-edge integrated machines so that it could better protect your delicate toes from chafing and blisters.
Last but not least, a pair of socks made of Lycra elastic cuff would support your long time comfortable wear without slipping.